TUM012 & TUM020
TUM012 is a modified polymer derivate that has the ability to spontaneously insert into cell membranes and form a tight coat that prevents plasma proteins and cells from reacting with the cell surface. By doing so, it protects ischemic cells from attack from the innate immune system.
TUM012 is also a platform molecule that can be used to further develop purpose-designed molecules that can protect the cell surface from specific damages. TUM020 is such a molecule that is developed to prevent damage particularly induced by warm ischemia.